Thousands of variables come in to play throughout the lifecycle of a pathology sample. Due to the sensitive nature of NGS any or all of these could effect the final sequencing quality.Using a suitable LIMS we can track as many or as few variables and feed it back into the system to continuously improve sequencing… Continue reading Tracking data to learn how to sequence
Tag: bioinformatics
Simple tool to count genomic base occurrences
This is a simple tools to count the occurence of each base at a specified genomic coordinate. It is simply to illustrate how to use the vast array of existing bioinformatics tools with some basic code of your own & without the need to use R for simple projects. Purpose: This piece of software uses… Continue reading Simple tool to count genomic base occurrences
Explanation of Molecular Modelling
The molecular dynamics method. By analysing a molecular system using physics, specifically the laws of motion and energy, one can model the movements of atoms within a 3d space or medium. By treating all atoms as ‘balls’ the motions can be calculated based on their interactions with other atoms. These interactions are derived using four main… Continue reading Explanation of Molecular Modelling
Introduction to Protein Folding
This is a basic description of what a protein is, what they become and the relevance of molecular modelling, as I didn’t really explain this in that blog. Cells are made of proteins. To build a protein, a cell uses the codes stored in its DNA to gather a group of Amino Acids (AA), a list if you will.… Continue reading Introduction to Protein Folding
Software Development & Bioinformatics 